“No sex, age, tissue or organs are spared from effects of Celiac Disease”

This is the #1 thing you should listen to if you or someone you love has Celiac Disease or Gluten Sensitivity. If you have people in your life or even one of your doctors who doubt the serious nature of it, have them listen too! (link at bottom)

2/27/17: Dr Allessio Fasano from the Center for Celiac Research is interviewed by Dr Theresa Nacassio on her radio show.

He talks about Celiac Disease, Gluten Sensitivity, the Microbiome, Leaky Gut, neurological complications in the brain and Autism, ADHD, Dimentia, Depression, Skin (Dermatitis Herpeteformis), Probiotics, Fecal Transplants and more!  He even talks about the Non-hybridized wheat myth, GMO’s, pesticides and more.

“No sex, age, tissue or organs are spared from the effects of Celiac Disease….”

The interview starts at  4min and 55 seconds on the timer in the link. You can fast forward through commercials too.  Dr Nacassio also has lots of other links to Dr Fasano’s interviews and talks on Celiac Disease up on her site.

Click Here

Guess Who Came to Dinner?

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Yes, that is Dr. Alessio Fasano, of the Center for Celiac Research and Treatment at Mass General. We had the pleasure of having Dr Fasano and his son back in the cafe for dinner this week. I was able to ask him a few questions in between.

I chose the questions that I get asked about the most by customers and those that affect me as well. My questions were about Gluten/Celiac Disease and it’s role in Autism, our Kidneys, our Skin and our Brains. I also asked about Glyphosate (Round Up) and it role, if any, in Celiac Disease.

Autism:

As many of you know, I have two nephews with Autism, so I have always been very interested in the connection between Celiac Disease, Gluten and Autism. Dr Fasano and Autism Speaks have been looking for a connection between Autism and Celiac Disease anf gluten . As of now, Dr. Fasano says that “about 5% of Children with Autism have Celiac Disease and most are Gluten Intolerant.”  Dr Fasano says “we know Gluten is a factor in Autism but we don’t know why.”

Glyphosate (Round Up) Sprayed on Crops:

Over the past year or so there has been a lot of information circulating on the web about Glyphosate, which is the ingredient used in Round Up weed killer.  It is also used on our crops to increase the yield before harvesting. Corn is one of those crops. So, I asked him about the connection, if any, between glyphosate (Round Up) being sprayed on our crops and if it is contributing to gut permeability (leaky gut) leaving us open to Celiac Disease.  He said that “we don’t know enough about it yet”. That tells me there are more studies that need to be done.

Celiac Reactions & Complications; Kidneys, Skin and Brain:

Kidneys: I also shared with Dr Fasano what my Nephrologist has told me about Celiac Disease and IgA Nephropathy (Berger’s Disease); the filters on my kidneys don’t work right and the little doors to the filters are getting the wrong message. So, I asked him what his thoughts were. He said;  “absolutely, it is very closely related to Celiac and sometimes the soldiers (immune cells), leave the intestine and attack other tissues, like those in the kidneys” (gallbladder, thyroid, brain, etc.).

I was telling him about my severe reaction after accidentally getting “glutened” in Jan 2015 and a new symptom I had after this episode. Normally for me, within a few hours I have severe acid reflux, the next morning I have a migraine followed by diarrhea and vomiting at the same time, then I get major bloating and knife like pains in my stomach. Then, within 24 hours I get flu like symptoms, severe fatigue and can not get off the couch.

Skin: On about day 3 or 4 I get a Dermatitis Herpetiformis (DH) rash and that itches and oozes and hurts and then the joint pain kicks in. I told him that I had a bad case of DH on my scalp, buttocks and arms and before I could say it he said: “it took 8 months to clear up”.  He was right on the money, I got “glutened” in January (I did a blog post about this) and it did not clear up until the end of August! (It cleared up because I had no further exposure to gluten. DH is most often misdiagnosed as eczema. It (the rash) can be biopsied for a Celiac Diagnosis, if you have this, bring it to you Gastroenterologist’s attention.)

Brain: By day 4 I had Ataxia (walking into walls, tripping and falling and speech issues).  New Symptom for Me: However, this time, by day 5 or so, I had MS like symptoms in my right arm and leg with heavy twitching. I had to pull over and it lasted for several minutes. He said “absolutely, it’s the inflammation; because it can affect the brain”.

I hope you found this information helpful. It was a pleasure having Dr. Fasano and his son back at One Dish Cuisine Cafe, Deli and Bakery! I know you want to know what Dr Fasano had for dinner. He and his son enjoyed our Eggplant Parm. Also, I know someone will say that the cafe looks different in the photo. It does look different because this photo was taken the last time he was here, for his book signing, in 2014.

 

Science Sounds The Alarm on Your Brain and Gluten

Science Sounds The Alarm About Your Brain and Gluten!   
From July 2015 Newsletter:
I think this is the area where we are going to see the most breakthroughs in medicine as it relates to celiac disease, gluten and our brains. I experience severe neurological symptoms when I accidentally ingest gluten as do many customers and one of my close friends.  Recently, after a severe glutening and neurological complications as part of her response, my friend saw her gastro; who sent her to a neurologist. The neurologist confirmed the complications from gluten exposure after her ran tests and ruled out MS.  So, it is great to see this being acknowledged by neurologists.
Allergic Living recently did an article; about the scientific proof and the devastating effects that gluten can have on your Brain. Dr. Marios Hadjivassiliou was the first to study this!  He said that the patients had “significantly less” brain density. The study showed that there were changes to the cerebellum (balance center) and to the thalamus which conveys sensory and motor signals to the cerebral cortex, and to areas of the brain associated with depression. For some it is just the inability to think clearly or being diagnosed with ADHD or Autism, when actually it could be Celiac Disease.

“We have to think of the bowel, not as where the disease occurs, but as an innocent bystander where the gluten crosses to do its damage,” Hadjivassiliou says. “It’s imperative that we change the mindset about celiac disease and brain dysfunction.”

10-30% of those with Celiac Disease have some form of neurological complications. It can be headaches, the inability to walk in a straight line, fumbled speech, walking into things, being off balance. The doctor even advocates for questions about headache and loss of balance to be asked when they go over a celiac symptom checklist! Those with bowel complaints are easy to diagnose, but many don’t have bowel complaints because their only symptoms are neurological!  Unfortunately for those without bowel issues; by the time they get to their neurologist it is too late because the nervous system does not regenerate like the intestines do.

When this is the case, the gluten free diet will only halt the damage in it’s tracks but not reverse the damage. This motor control condition is called Gluten Ataxia; where grey matter accumulates on the brain and can shrink areas of the brain! The gluten free diet can halt additional damage, but it does not mean they will be able to walk again.

“With grey matter damage, you may have balance issues, problems speaking or sensory symptoms. With white matter damage, you may suffer headaches as intense as migraines, have tingling sensations in your arms and legs, experience extreme fatigue or suffer from insomnia.”

While most mild cases won’t show up on brain scans, Hadjivassiliou’s research shows that repeated incidents of getting “glutened” or “cheating”  on the diet can lead to more serious, long-term brain effects.

Dr Dan Leffler of Beth Israel Deaconess Medical Center in Boston is studying this too and said:
“This is an issue that is very real and very common and the big problem is misdiagnosis because it just doesn’t get enough attention.”

Gluten actually causes increased intestinal permeability by inducing a compound called zonulin to be released. Zonulin causes tight junctions to not be so tight…thus increased intestinal permeability. The large gluten molecule is able to molecularly interact with our body and cause our body to increase zonulin production…zonulin then causes increased permeability…and then this large gluten molecule is able to get into our body. The gluten molecule is too large to normally enter our body therefore when it does gain access to our body through our small intestine, our immune system perceives it as a threat and for some people it starts the cascade of a chronic disease.

So how does this all come together???? Thanks to Dr Alessio Fasano at the Center for Celiac Research, we know that gluten causes increased intestinal permiability (little holes in the walls of the intestine) which causes a compound “Zonulin” to be released which allows the gluten molecule to get into our bloodstream thru the little holes in our intestines. Once it gets there our immune system sees it as a “threat” and for some it causes a whole list of chronic diseases. Also, zonulin causes cellular reactions throughout the body, not just within the gut. For some people this will never happen, for others it will!

Check out my blog under “brain” for past articles from newsletters where I wrote about this as well!

My Thoughts on “Grain Brain”; by David Perlmutter, MD

Many customers, while dining in my cafe, have asked me what I thought of Grain Brain, written by renowned neurologist, David Perlmutter, MD.

First, I will say that the book is excellent and a must read for everyone, especially if you or your family are touched by Celiac, gluten sensitivity, autism, dementia, alzheimer’s, stroke or heart disease! Dr Perlmutter goes into great detail about the care and feeding of your brain.  Showing, through research, studies and clinical experience exactly how healthy carbohydrates; such as whole grains and sugar can cause dementia, ADHD, epilepsy, anxiety, headaches, depression and more.

I made some some notes while reading the book that you might find of interest. First and foremost, Dr Perlmutter believes that Gluten Sensitivity is the real issue at hand and that Celiac Disease is an extreme manifestation of Gluten Sensitivity.

Gluten Sensitivity:

-Celiac Disease is an extreme manifestation of gluten sensitivity; the most severe reaction to gluten.

-1 in 30 people have Celiac Disease as estimated by Dr Perlmutter, although experts say 1 in 200 or 1 in 131; many are not diagnosed.

-1 in 4 people are vulnerable to Celiac Disease due to genetics alone and those of northern European descent are more susceptible.

-A person’s genes determine gluten sensitivity or severity, meaning there is a very wide spectrum to it.

-Gluten does not just harm the gut, once the genes are triggered, sensitivity to gluten is lifelong condition that can affect the skin, mucous membranes and the mouth.  Gluten reactions can involve any organ in the body including the brain, even if the gut is fine.

-The brain is at great risk if a person is gluten sensitive.

-Food Sensitivities are usually a response from the immune system.  The presence of gluten basically disables the body’s immune system and it can’t fully support the body’s natural defenses.

-About 45% of people with ASD (autism spectrum disorders) have gastrointestinal problems. There is an increased prevalence of celiac in pediatric cases of autism, compared to the general population.

-People with Celiac Disease may be at increased risk for developmental delays, tic disorders, learning disorders and ADHD.

-Depression and anxiety are often severe in those with gluten sensitivity.

-He dispels the myth that all fat is bad for you. Low cholesterol can affect mood and put your brain at risk. Your brain needs fat and is made of fat.

-“Routine lab tests for Celiac Disease are not sensitive enough to uncover gluten sensitivity, so don’t bother with them”. (I take issue with this, you need to know if you have Celiac first, then if negative, look for gluten sensitivity. No wonder 83% of those with Celiac are said to be undiagnosed!)

-Inflammation is the cornerstone to brain disease. He goes into great detail about dementia and alzheimer’s disease and the role gluten plays along with sugar, statin drugs, strokes, diabetes and so much more. Much time is devoted to talking about how all carbohydrates; grains and sugar are causing us problems (inflammation) and has lots of studies and clinical experience referenced in the book. There is also great information in the book about vitamin deficiencies, leaky gut and more.

I think this book is a must read; or buy it on CD and listen to it on a long car ride. I think it is eye opening and saw so many of my health issues highlighted in this book;Grain Brain it has convinced me to tweak my GF diet a bit. (I can attest that gluten does affect the brain! Read my blog post about when I was “glutened” on vacation.)

From Gut to Brain, Ataxia and More

This is from our Feb 2012 Newsletter. If you think you have gluten ataxia or balance or coordination issues, speech impairment or any brain involvement when ingesting gluten, this is great information for you to have and it may be worth taking it to your doctor if they don’t seem to be listening to you. This has case studies from Gastroenterologists and Neurologists.

http://www.etseq.urv.es/cdmedics/pdfs/Celiac%20disease%20from%20gut%20to%20brain.pdf

Amazing MRI’s of the brain showing before and after of a person with rapid onset of Ataxia over a period of 15 months.

http://celiacbrain.com/?p=86